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Structure and Function in Cell Signalling, by John Nelson
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"This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions … the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009
"A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information." –Australian Biochemist, August 2009
"From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." –Doody's, January 2009
This text is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities – the ‘nuts and bolts’ of cellular information exchange.
With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.
- An accessible introduction to the complex field of cell signalling
- Interacts with RasMol software – freely downloadable for viewing structures in 3D
- Includes exercises and clear instructions in the use of RasMol
- Well illustrated in full colour throughout
Structure and Function in Cell Signalling is an invaluable resource to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book provides a clear, accessible introduction to this rapidly expanding field.
- Sales Rank: #2571037 in Books
- Published on: 2008-08-04
- Original language: English
- Number of items: 1
- Dimensions: 9.60" h x .75" w x 6.65" l, 1.95 pounds
- Binding: Paperback
- 410 pages
Review
"Richly illustrated with full-color molecular graphics (created by RasMol, a freeware molecular visualization program), Structure and Function in Cell Signaling provides a clear, engaging introduction to signal transduction. Each of the book's 10 chapters includes tables and charts in color to illustrate signal transduction pathways and genetic relationships between signal transduction molecules. Nelson (Queens Univ. Belfast, UK) provides enough background information to make this complex subject accessible even to beginning students. Readers can easily re-create all of the molecular graphics for themselves in an interactive format by following simple instructions included in the appendix. Signal transduction has applications in all of the biological sciences. Thus, students in cell biology, biochemistry, immunology, molecular genetics, and other life sciences will all find much valuable information in this work. Summing Up: Highly recommended. Academic libraries, all levels."(Choice, February 2009)
"From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." (Doody's, January 2009)
From the Back Cover
Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.
With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.
Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.
- An accessible introduction to the complex field of cell signalling.
- Interacts with RasMol software - freely downloadable for viewing structures in 3D.
- Includes exercises and clear instructions in the use of RasMol.
- Well illustrated in full colour throughout.
Structure and Function in Cell Signalling will prove invaluable to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book will provide a clear, accessible introduction to this rapidly expanding field.
Most helpful customer reviews
7 of 8 people found the following review helpful.
Good introduction to cellular signaling
By Nancy
There are not very many books available that try to cover cellular signaling at an introductory level, but this one does a very good job of it. It is well written and at a level appropriate for people with a range of backgrounds. I think that as long as you've had a couple of semesters of biochemistry or cell or molecular biology, you should be able to understand the material. I really liked the way the book was organized, and I appreciated the inclusion of quantitative approaches to signaling. Although I don't use RasMol, the emphasis on protein structure was appreciated and the book makes it easy to use other free programs to examine the structures of the proteins that are discussed.
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